Description

1-Piperidinecarboxylic Acid, 4-[(1S)-1-Aminoethyl]-, Phenylmethyl Ester is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high biological relevance. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry for efficacy.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained amino acid analog for creating novel peptide-like structures with enhanced metabolic stability.
• Asymmetric Catalysis Ligand Precursor: A potential precursor for chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Chemical Biology Probe Development: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-[(1S)-1-Aminoethyl]-, Phenylmethyl Ester
CAS No.	1415300-01-4
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	Benzyl (4-[(1S)-1-aminoethyl]piperidine-1-carboxylate; (S)-Benzyl 4-(1-aminoethyl)piperidine-1-carboxylate; 4-[(1S)-1-Aminoethyl]-1-piperidinecarboxylic Acid Phenylmethyl Ester; (S)-1-((Benzyloxy)carbonyl)-4-(1-aminoethyl)piperidine; (S)-Cbz-4-(1-aminoethyl)piperidine; (S)-N-Cbz-4-(1-aminoethyl)piperidine; 1415300-01-4; CAS 1415300-01-4
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid, 4-[(1S)-1-Aminoethyl]-, Phenylmethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against comprehensive specifications, including chiral purity and impurity profiling. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.