Description

5-Methyl-2-Nitro-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolo-pyrazine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• Drug Discovery & Medicinal Chemistry: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in early-stage R&D.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production of target molecules under current Good Manufacturing Practice (cGMP) guidelines.
• Chemical Biology Research: Acts as a tool compound or a labeled probe for investigating enzyme mechanisms and protein-ligand interactions.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	5-Methyl-2-Nitro-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One
CAS No.	1408327-48-9
Molecular Formula	C8H8N4O3
Molecular Weight	208.18 g/mol
Synonyms	5-Methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-4-one; 5-Methyl-2-nitro-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-4-one; 1408327-48-9; 5-Methyl-2-nitro-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazin-4-one; Pyrazolo[1,5-a]pyrazin-4(5H)-one, 6,7-dihydro-5-methyl-2-nitro-; SCHEMBL21806227; BCP31933
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Nitro-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.