Description

2-Piperazinemethanol, 5-Methyl-, (2R,5R)- is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its stereochemistry is critical for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules, particularly for applications in medicinal chemistry and asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity in fine chemical production.
• Agrochemical Research: Serves as a building block for developing novel, stereochemically-defined crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in chemical research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	2-Piperazinemethanol, 5-Methyl-, (2R,5R)-
CAS No.	1404048-45-8
Molecular Formula	C6H14N2O
Molecular Weight	130.19 g/mol
Synonyms	(2R,5R)-5-Methyl-2-piperazinemethanol; (2R,5R)-5-Methylpiperazine-2-methanol; (2R,5R)-2-(Hydroxymethyl)-5-methylpiperazine; (2R,5R)-1,4-Diazacyclohexane-2-methanol, 5-methyl-; (2R,5R)-5-Methyl-1,4-diazacyclohexane-2-methanol; (2R,5R)-5-Methyl-2-piperazinemethenol; 2-Piperazinemethanol, 5-methyl-, (2R,5R)-
EINECS	Contact for details

Quality Control

Our 2-Piperazinemethanol, 5-Methyl-, (2R,5R)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.