Description

2-(4-Boc-Piperazinyl)-2-(4-Ethoxylphenyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a protected piperazine moiety and a functionalized acetic acid group for versatile coupling reactions. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new chemical entities.
• Peptidomimetic Synthesis: Serves as a crucial component for constructing peptide-like molecules with enhanced metabolic stability.
• API Development: Integral in the multi-step synthesis of complex Active Pharmaceutical Ingredients requiring a protected heterocyclic amine.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Chemical Biology Probes: Useful for creating labeled or tagged compounds for target identification and validation studies.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(4-Ethoxylphenyl)Acetic Acid
CAS No.	1400644-21-4
Molecular Formula	C19H28N2O5
Molecular Weight	364.44 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(4-ethoxyphenyl)acetic acid; 2-(4-Boc-1-piperazinyl)-2-(4-ethoxyphenyl)acetic acid; 2-(4-Ethoxyphenyl)-2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]acetic acid; Boc-Pip-OEt-Ph-Gly-OH; (4-Ethoxyphenyl)[4-[(2-methyl-2-propanyl)oxycarbonyl]-1-piperazinyl]acetic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(4-Ethoxylphenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to maintain stability. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.