Description

1-(3-Fluoro-2-Methoxyphenyl)Piperazine Hydrochloride is a high-purity, synthetically derived chemical building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality raw materials for drug discovery and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate in the development and scale-up of API manufacturing processes.
• Biochemical Research: Employed as a tool compound in pharmacological studies to investigate receptor interactions and signaling pathways.
• Custom Synthesis: A building block for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	1-(3-Fluoro-2-Methoxyphenyl)Piperazine Hydrochloride
CAS No.	1396762-35-8
Molecular Formula	C11H15ClFN2O
Molecular Weight	245.70 g/mol
Synonyms	1-(3-Fluoro-2-methoxyphenyl)piperazine hydrochloride; 3-Fluoro-2-methoxyphenylpiperazine hydrochloride; 1-(3-Fluoro-2-methoxyphenyl)piperazine HCl; Piperazine, 1-(3-fluoro-2-methoxyphenyl)-, hydrochloride (1:1); 1396762-35-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) are available upon request and can be tailored to meet specific customer or regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.