Description

1-(2-Fluoro-6-Methoxyphenyl)Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1396762-14-3. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable, high-quality building block for complex synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D settings.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial building block in the multi-step synthesis of complex APIs targeting specific receptors.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	1-(2-Fluoro-6-Methoxyphenyl)Piperazine Hydrochloride
CAS No.	1396762-14-3
Molecular Formula	C11H16ClFN2O
Molecular Weight	246.71 g/mol
Synonyms	1-(2-Fluoro-6-methoxyphenyl)piperazine hydrochloride; 2-Fluoro-6-methoxy-1-piperazin-1-ylbenzene hydrochloride; 1-(2-Fluoro-6-methoxyphenyl)piperazine HCl; 1-(2-Fluoro-6-methoxyphenyl)piperazine monohydrochloride; 2-Fluoro-6-methoxyphenylpiperazine hydrochloride; Piperazine, 1-(2-fluoro-6-methoxyphenyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports the needs of research through to development-scale cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.