Description

(1E)-3-Methoxy-8,12-Epoxygermacra-1,7,10,11-Tetraen-6-One CAS NO 1393342-06-7 is a specialized sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for research and development in advanced pharmaceutical and agrochemical synthesis. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for its unique structural framework.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents, particularly in anti-inflammatory and anticancer research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its natural product-inspired structure for bioactivity.
• Natural Product Synthesis: A valuable precursor for the total or semi-synthesis of complex germacranolide-type natural products in academic and industrial laboratories.
• Biochemical Research: Employed as a reference standard or probe molecule in pharmacological studies to investigate biological pathways and enzyme interactions.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	(1E)-3-Methoxy-8,12-Epoxygermacra-1,7,10,11-Tetraen-6-One
CAS No.	1393342-06-7
Molecular Formula	C16H18O4
Molecular Weight	274.31 g/mol
Synonyms	(1E)-3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one; 8,12-Epoxy-3-methoxygermacra-1(10),7,11-trien-6-one; Germacra-1(10),7,11-trien-6-one, 8,12-epoxy-3-methoxy-, (1E)-; 3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one; Sesquiterpene lactone derivative; Epoxygermacratrienone derivative
EINECS	Contact for details

Quality Control

Our (1E)-3-Methoxy-8,12-Epoxygermacra-1,7,10,11-Tetraen-6-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure high consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.