Description

5-Amino-1-Boc-2-Methylpiperidine is a high-purity, protected piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and versatile intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potent drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperidine scaffold for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Bioactive Molecules: Incorporated into the backbone of peptidomimetic compounds and other bioactive molecules to modulate pharmacokinetic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	5-Amino-1-Boc-2-Methylpiperidine
CAS No.	1392473-06-1
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-5-Amino-2-Methylpiperidine; tert-Butyl 5-Amino-2-Methylpiperidine-1-carboxylate; 2-Methyl-5-Aminopiperidine-1-carboxylic Acid tert-Butyl Ester; 5-Amino-2-methyl-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 2-Methyl-5-aminopiperidine-1-Boc; Boc-5-Amino-2-Methylpiperidine
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Boc-2-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.