Description

(S)-Ethyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate is a high-purity, chiral organophosphorus compound designed for advanced synthetic applications. This specialty chemical serves as a critical building block or chiral auxiliary in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control and high functional group tolerance in their synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological or metabolic disorders.
• Asymmetric Synthesis Catalyst/ Ligand: Used as a component in catalyst systems or as a chiral ligand for transition metal catalysis to induce enantioselectivity.
• Agrochemical Research: Intermediate in the development of novel, enantiomerically pure herbicides, insecticides, or plant growth regulators.
• Peptidomimetic & Prodrug Synthesis: Building block for creating phosphonamidate and phosphonate analogs of amino acids, useful in prodrug strategies and enzyme inhibitor design.
• Material Science Research: Potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Used to develop activity-based probes or labeled compounds for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(S)-Ethyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate
CAS No.	1392015-05-2
Molecular Formula	C17H15F5NO5P
Molecular Weight	463.27 g/mol
Synonyms	Ethyl (2S)-2-[[(S)-(Perfluorophenoxy)-phenoxy-phosphoryl]amino]propanoate; L-Alanine, N-[(perfluorophenoxy)phenoxyphosphinyl]-, ethyl ester, (S)-; (S)-Ethyl 2-(((S)-(Pentafluorophenoxy)(phenoxy)phosphoryl)amino)propanoate; Phosphoramidic acid, N-[(1S)-1-(ethoxycarbonyl)ethyl]-, (S)-, P-phenyl P-(2,3,4,5,6-pentafluorophenyl) ester; Chiral Phosphonamidate Ester; Alanine-derived Phosphoramidate
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 2-(((S)-(Perfluorophenoxy)(Phenoxy)Phosphoryl)Amino)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR (¹H, ¹³C, ³¹P), and mass spectrometry, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere such as nitrogen or argon to maximize stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.