Description

Piperazine, 1-(Tetrahydro-3-Furanyl)-Hcl Salt is a specialized piperazine derivative salt, a key building block in modern pharmaceutical synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D and manufacturing companies need this high-purity intermediate to ensure the efficacy and safety of their final drug products.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for neurological and psychiatric drug candidates.
• Organic Synthesis Reagent: Used in research and development for constructing complex nitrogen-containing heterocycles, leveraging the piperazine and tetrahydrofuran moieties.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Precursor for Fine Chemicals: Employed in the multi-step synthesis of other high-value, specialized fine chemicals and advanced intermediates.

Basic Information

Item	Detail
Product Name	Piperazine, 1-(Tetrahydro-3-Furanyl)-Hcl Salt
CAS No.	1391733-05-3
Molecular Formula	C9H19ClN2O
Molecular Weight	206.71 g/mol
Synonyms	1-(Tetrahydrofuran-3-yl)piperazine hydrochloride; 3-(Piperazin-1-yl)tetrahydrofuran hydrochloride; Tetrahydro-3-furanylpiperazine HCl; N-(Tetrahydrofuran-3-yl)piperazine hydrochloride; 1-(Oxolan-3-yl)piperazine hydrochloride; Piperazine, 1-(tetrahydro-3-furanyl)-, hydrochloride; (Tetrahydrofuran-3-yl)piperazine hydrochloride
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(Tetrahydro-3-Furanyl)-Hcl Salt is manufactured under strict quality management systems suitable for pharmaceutical intermediate applications. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.