Description

(S)-Methyl 4-(Piperidin-2-Yl)Benzoate Hydrochloride CAS NO 1391547-09-3 is a high-purity chiral intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, particularly those targeting neurological and cardiovascular pathways. It is primarily needed by R&D laboratories, process chemists, and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules requiring a specific (S)-configured piperidine-benzoate moiety.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in studies exploring new catalytic methodologies.
• Chemical Biology & Proteomics: Utilized as a scaffold for designing molecular probes to study enzyme function and protein-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	(S)-Methyl 4-(Piperidin-2-Yl)Benzoate Hydrochloride
CAS No.	1391547-09-3
Molecular Formula	C14H20ClNO2
Molecular Weight	269.77 g/mol
Synonyms	(S)-Methyl 4-(2-Piperidinyl)benzoate hydrochloride; Methyl (S)-4-(piperidin-2-yl)benzoate HCl; (S)-Methyl 4-(2-piperidyl)benzoate hydrochloride; 4-[(2S)-Piperidin-2-yl]benzoic acid methyl ester hydrochloride; (S)-Methyl 4-(piperidin-2-yl)benzoate monohydrochloride; (S)-Methyl 4-(2-piperidinyl)benzoate hydrochloride; Benzoic acid, 4-(2S)-2-piperidinyl-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Methyl 4-(Piperidin-2-Yl)Benzoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.