Description

Piperidine, 2-(4-Bromophenyl)-, Hydrochloride (1:1), (2R)- is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its core value lies in providing a stereochemically defined piperidine scaffold functionalized with a bromophenyl group, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where specific stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in creating advanced, enantiomerically pure crop protection agents and pesticides.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed as a molecular probe or scaffold in studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring a defined (2R) stereocenter.
• Academic Research: Used in universities and research institutes for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Piperidine, 2-(4-Bromophenyl)-, Hydrochloride (1:1), (2R)-
CAS No.	1391389-94-8
Molecular Formula	C11H14BrN•HCl
Molecular Weight	276.60 g/mol
Synonyms	(2R)-2-(4-Bromophenyl)piperidine hydrochloride; (R)-2-(4-Bromophenyl)piperidine hydrochloride; (R)-2-(p-Bromophenyl)piperidine HCl; 2-(4-Bromophenyl)piperidine hydrochloride, (R)-; (R)-2-(4-Bromophenyl)piperidinium chloride; (R)-2-(4-Bromophenyl)piperidine monohydrochloride; 2-(4-Bromophenyl)piperidine HCl, (R)-enantiomer; (R)-4-Bromo-α-piperidinobenzyl alcohol hydrochloride (tautomeric form)
EINECS	Contact for details

Quality Control

Our Piperidine, 2-(4-Bromophenyl)-, Hydrochloride (1:1), (2R)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.