Description

1-[(S)-n-tert-Boc-n-Methyltyrosyl]-4-Phenylpiperazine is a sophisticated, non-natural amino acid derivative designed for advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate in the synthesis of complex bioactive molecules, particularly peptides and peptidomimetics. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require high-purity, well-characterized intermediates for drug discovery programs targeting neurological disorders, metabolic diseases, and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic peptides and small molecule drugs.
• Peptidomimetic Research: Used to construct peptide analogs with enhanced metabolic stability, bioavailability, and receptor selectivity.
• Neurological Drug Discovery: Serves as a precursor for compounds targeting GPCRs (G-protein coupled receptors) and other neurological targets.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the creation of labeled or tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A requested building block for custom synthesis services catering to specialized R&D needs.

Basic Information

Product Name	1-[(S)-n-tert-Boc-n-Methyltyrosyl]-4-Phenylpiperazine
CAS No.	1391068-29-3
Molecular Formula	C26H35N3O4
Molecular Weight	453.58 g/mol
Synonyms	(S)-1-((tert-Butoxycarbonyl)(methyl)amino)-3-(4-hydroxyphenyl)-2-(4-phenylpiperazine-1-yl)propyl propanoate; Boc-N-Me-Tyr(4-Phenylpiperazine)-OH; N-Boc-N-Methyl-4-Phenylpiperazine-1-yl-L-tyrosine; tert-Butyl (S)-(1-((4-hydroxyphenyl)-3-oxo-2-(4-phenylpiperazin-1-yl)propyl)(methyl)carbamate; 1-[(S)-N-tert-Butoxycarbonyl-N-Methyltyrosyl]-4-Phenylpiperazine; Boc-N-Me-Tyr(Ppz)-OH
EINECS	Contact for details

Quality Control

Our 1-[(S)-n-tert-Boc-n-Methyltyrosyl]-4-Phenylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.