Description

1-[4-[4-(2,3-Dichlorophenyl)Piperazin-1-Yl]Butyl]-7-Hydroxy-1,2,3,4-Tetrahydro-\Ncarbostyril is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound, with CAS number 1391054-74-2, is valued for its complex heterocyclic structure, which serves as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly within the central nervous system (CNS) and receptor-targeted drug categories.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates targeting specific biological receptors.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Biochemical Research: Utilized in vitro studies to investigate ligand-receptor interactions and pharmacological mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for preclinical research.

Basic Information

Product Name	1-[4-[4-(2,3-Dichlorophenyl)Piperazin-1-Yl]Butyl]-7-Hydroxy-1,2,3,4-Tetrahydro-\Ncarbostyril
CAS No.	1391054-74-2
Molecular Formula	C23H27Cl2N3O2
Molecular Weight	448.39 g/mol
Synonyms	7-Hydroxy-1-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-3,4-dihydro-2(1H)-quinolinone; Aripiprazole Related Compound; OPC-14597 Derivative; 1,2,3,4-Tetrahydro-7-hydroxy-1-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-2-oxoquinoline; 7-Hydroxy Aripiprazole Intermediate; 2(1H)-Quinolinone, 3,4-dihydro-7-hydroxy-1-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyl]-
EINECS	Contact for details

Quality Control

Our 1-[4-[4-(2,3-Dichlorophenyl)Piperazin-1-Yl]Butyl]-7-Hydroxy-1,2,3,4-Tetrahydro-\Ncarbostyril is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.