Description

1-Methyl-4-(3-Pyrrolidinyl)-Piperazine 3Hcl CAS NO 1390654-38-2 is a high-purity, trihydrochloride salt derivative of a substituted piperazine, a versatile nitrogen-containing heterocycle. This compound is valued as a critical pharmaceutical intermediate and research chemical for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D and production teams in the pharmaceutical and biotechnology sectors for its utility in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR) and develop new therapeutic candidates.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis or biochemical assays.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	1-Methyl-4-(3-Pyrrolidinyl)-Piperazine 3Hcl
CAS No.	1390654-38-2
Molecular Formula	C9H21Cl3N3 (as trihydrochloride salt)
Molecular Weight	Contact for details
Synonyms	1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride; 3-(4-Methylpiperazin-1-yl)pyrrolidine trihydrochloride; 1-Methyl-4-(3-pyrrolidinyl)piperazine hydrochloride (1:3); 1-Methyl-4-(pyrrolidin-3-yl)piperazine hydrochloride; 1-Methyl-4-(3-pyrrolidinyl)piperazine trihydrochloride; 1390654-38-2; 3-Piperazin-1-yl-pyrrolidine trihydrochloride (methyl substituted)
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-(3-Pyrrolidinyl)-Piperazine 3Hcl is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.