Description

Methyl 3-Azabicyclo[3.1.1]heptane-6-carboxylate hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial synthesis of complex target molecules.
• Academic Research: Employed in university and institutional labs for studying novel synthetic methodologies and heterocyclic chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	Methyl 3-Azabicyclo[3.1.1]heptane-6-carboxylate Hydrochloride
CAS No.	1389264-36-1
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	6-(Methoxycarbonyl)-3-azabicyclo[3.1.1]heptane hydrochloride; Methyl 3-azabicyclo[3.1.1]heptane-6-carboxylate HCl; 3-Azabicyclo[3.1.1]heptane-6-carboxylic acid, methyl ester, hydrochloride; 1389264-36-1; 3-Azabicyclo[3.1.1]heptane-6-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 3-Azabicyclo[3.1.1]heptane-6-carboxylate hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions if the container is opened repeatedly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.