Description

(R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One CAS NO 1383146-20-0 is a chiral piperazinone derivative, a high-value advanced pharmaceutical intermediate (API) and building block. Its significance lies in its stereospecific structure, which is critical for imparting desired biological activity in complex drug molecules. This compound is primarily needed by pharmaceutical R&D and manufacturing organizations engaged in the synthesis of novel therapeutics, particularly in the areas of central nervous system (CNS) and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Serves as a precursor or chiral auxiliary in stereoselective chemical transformations.
• Protease Inhibitor Research: Potential application in the development of inhibitors targeting specific enzymes.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of clinical trial materials.
• Academic & Industrial Research: Utilized in chemical and pharmacological research programs exploring new therapeutic entities.

Basic Information

Product Name	(R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One
CAS No.	1383146-20-0
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	(R)-4-(2,4-Dimethoxybenzyl)-3-methylpiperazin-2-one; (R)-3-Methyl-4-(2,4-dimethoxybenzyl)piperazin-2-one; (2R)-4-[(2,4-Dimethoxyphenyl)methyl]-3-methyl-2-piperazinone; (R)-3-Methyl-4-(2,4-dimethoxybenzyl)-2-piperazinone; 1383146-20-0; (R)-enantiomer of 4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
EINECS	Contact for details

Quality Control

Our (R)-4-(2,4-Dimethoxybenzyl)-3-Methylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and may be hygroscopic; therefore, containers should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.