Description

2-Bromo-5-(Bromomethyl)Pyrazine is a high-purity, multi-functional brominated pyrazine building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, enabling selective functionalization and the construction of complex heterocyclic scaffolds. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for creating tagged molecules or covalent inhibitors for target identification and proteomics studies.
• Custom Synthesis and Scale-up: Provides a versatile starting point for contract research organizations (CROs) and custom synthesis manufacturers.

Basic Information

Product Name	2-Bromo-5-(Bromomethyl)Pyrazine
CAS No.	1382866-97-8
Molecular Formula	C5H4Br2N2
Molecular Weight	251.91 g/mol
Synonyms	5-(Bromomethyl)-2-bromopyrazine; 2-Bromo-5-(bromomethyl)pyrazine; Pyrazine, 2-bromo-5-(bromomethyl)-; 2,5-Dibromomethylpyrazine (common name); 1382866-97-8; AI3-32955; ZINC000253949793; BDBM50389325; AKOS005259093; SCHEMBL15506227; CTK8C4794; MolPort-044-690-202
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Bromomethyl)Pyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.