Description

3-Chloro-2-(Hydroxymethyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of focused compound libraries for high-throughput screening.
• Process Development & Scale-Up: Used in the optimization and kilogram-scale production of target molecules during the transition from laboratory to pilot plant and commercial manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for the study of novel heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	3-Chloro-2-(Hydroxymethyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One
CAS No.	1382786-15-3
Molecular Formula	C8H8ClN3O2
Molecular Weight	213.62 g/mol
Synonyms	3-Chloro-2-(hydroxymethyl)-5,6-dihydropyrazolo[1,5-a]pyrazin-4(7H)-one; 3-Chloro-2-(hydroxymethyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-4-one; 1382786-15-3; 3-Chloro-2-hydroxymethyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one; Pyrazolo[1,5-a]pyrazin-4(5H)-one, 3-chloro-2-(hydroxymethyl)-6,7-dihydro-
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Hydroxymethyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazin-4(5H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.