Description

2-Chloro-4-[4-(2-Hydroxyethyl)Piperazino]Benzaldehyde is a versatile and high-value chemical intermediate characterized by its unique benzaldehyde core functionalized with a chloro substituent and a piperazine ring bearing a hydroxyethyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine moiety's prevalence in bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the chloro and aldehyde groups offer sites for further chemical modification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Employed in the research of organic semiconductors and charge-transport materials, where its conjugated system can be extended.
• Chemical Biology Probes: Utilized to develop fluorescent probes or affinity tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical component for custom synthesis houses serving the life sciences sector, enabling the production of bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-4-[4-(2-Hydroxyethyl)Piperazino]Benzaldehyde
CAS No.	1381944-80-4
Molecular Formula	C₁₃H₁₇ClN₂O₂
Molecular Weight	268.74 g/mol
Synonyms	2-Chloro-4-(4-(2-hydroxyethyl)piperazin-1-yl)benzaldehyde; 4-(4-(2-Hydroxyethyl)-1-piperazinyl)-2-chlorobenzaldehyde; 2-Chloro-4-[4-(2-hydroxyethyl)-1-piperazinyl]benzaldehyde; Benzaldehyde, 2-chloro-4-[4-(2-hydroxyethyl)-1-piperazinyl]-; 1-[3-Chloro-4-formylphenyl]-4-(2-hydroxyethyl)piperazine; 1381944-80-4; 2-Chloro-4-(4-(2-hydroxyethyl)piperazine-1-yl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-[4-(2-Hydroxyethyl)Piperazino]Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as nitrogen or argon in a sealed container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.