Description

tert-Butyl n-(((4-(6-Methyl-1,2,4,5-Tetrazin-3-Yl)Phenyl)Methyl)Carbamate is a specialized heterocyclic compound featuring a tetrazine core, a key functional group in modern bioorthogonal chemistry. This high-purity intermediate is critical for researchers and manufacturers requiring precise, reliable building blocks for advanced applications. It is primarily utilized in the development of novel pharmaceuticals, bioconjugation reagents, and materials science research where controlled, rapid, and selective chemical ligation is essential.

Application

• Bioorthogonal Chemistry Reagent: Serves as a key component in inverse electron-demand Diels-Alder (IEDDA) click chemistry for bioconjugation.
• Pharmaceutical Intermediate: Used in the synthesis of targeted drug conjugates, antibody-drug conjugates (ADCs), and radiopharmaceuticals.
• Proteomics & Biomarker Labeling: Enables site-specific labeling of proteins, peptides, and other biomolecules for imaging and diagnostic applications.
• Materials Science & Polymer Chemistry: Facilitates the surface functionalization of nanoparticles, polymers, and hydrogels for creating smart materials.
• Chemical Biology Tool Development: A foundational building block for creating novel probes and sensors for live-cell imaging and activity-based profiling.
• Precision Agrochemicals: Employed in research for developing targeted delivery systems for agrochemicals.

Basic Information

Product Name	tert-Butyl n-(((4-(6-Methyl-1,2,4,5-Tetrazin-3-Yl)Phenyl)Methyl)Carbamate
CAS No.	1380500-86-6
Molecular Formula	C16H20N6O2
Molecular Weight	328.37 g/mol
Synonyms	Boc-Tetrazine-PEG1-Benzylamine; tert-Butyl (4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl)carbamate; 3-(4-((((tert-Butoxy)carbonyl)amino)methyl)phenyl)-6-methyl-1,2,4,5-tetrazine; TCO-Boc Amine Tetrazine; Tetrazine-Boc-NH-PEG1-Benzyl; 6-Methyl-3-[4-[[(tert-butoxycarbonyl)amino]methyl]phenyl]-1,2,4,5-tetrazine; Boc-Amine-PEG1-Tetrazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical-grade intermediates. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical quality attributes are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and should be handled under controlled conditions to maintain its reactivity and purity. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Red to purple solid or powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.