Description

4-(3-Chloropyrazin-2-Yl)-2-Methylbut-3-Yn-2-Ol is a specialized organic building block featuring a chloropyrazine core and an alkyne alcohol functional group. This compound is valued for its unique molecular architecture, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing complex heterocyclic molecules, such as potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other heterocyclic-based therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyrazine moiety for biological activity.
• Chemical Synthesis: Serves as a versatile building block in organic synthesis for constructing complex molecular scaffolds via cross-coupling reactions (e.g., Sonogashira) or click chemistry.
• Material Science Research: Potential precursor for the development of functional organic materials, such as ligands for catalysts or components in organic electronics.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory research in synthetic organic chemistry.

Basic Information

Product Name	4-(3-Chloropyrazin-2-Yl)-2-Methylbut-3-Yn-2-Ol
CAS No.	1378802-34-6
Molecular Formula	C9H9ClN2O
Molecular Weight	196.63 g/mol
Synonyms	2-Methyl-4-(3-chloropyrazin-2-yl)but-3-yn-2-ol; 4-(3-Chloro-2-pyrazinyl)-2-methyl-3-butyn-2-ol; 3-Butyn-2-ol, 4-(3-chloro-2-pyrazinyl)-2-methyl-; 2-Methyl-4-(3-chloropyrazin-2-yl)-3-butyn-2-ol; 4-(3-Chloropyrazin-2-yl)-2-methylbut-3-yn-2-ol
EINECS	Contact for details

Quality Control

Our 4-(3-Chloropyrazin-2-Yl)-2-Methylbut-3-Yn-2-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with your specified requirements. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.