Description

5-Amino-6-Chloro-Pyrazine-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazine core enables the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: A versatile precursor for creating complex heterocyclic compounds in academic and industrial R&D laboratories.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-Amino-6-Chloro-Pyrazine-2-Carboxylic Acid Methyl Ester
CAS No.	1378678-66-0
Molecular Formula	C7H7ClN4O2
Molecular Weight	214.61 g/mol
Synonyms	Methyl 5-Amino-6-chloropyrazine-2-carboxylate; 6-Chloro-5-aminopyrazine-2-carboxylic acid methyl ester; 5-Amino-6-chloro-2-pyrazinecarboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 5-amino-6-chloro-, methyl ester; Methyl 5-amino-6-chloropyrazinecarboxylate; 5-Amino-6-chloropyrazine-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Chloro-Pyrazine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.