Description

2-(6-Chloropyrazin-2-Yl)Acetonitrile is a versatile and high-value pyrazine-based nitrile building block, essential for constructing complex heterocyclic scaffolds in advanced chemical synthesis. Its core value lies in enabling precise molecular modifications critical for developing novel active ingredients in the pharmaceutical and agrochemical sectors. This intermediate is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides requiring specific pyrazine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring chloropyrazine functionalization.
• Academic and Industrial R&D: Fundamental building block for exploratory chemistry in medicinal and synthetic organic chemistry laboratories.

Basic Information

Product Name	2-(6-Chloropyrazin-2-Yl)Acetonitrile
CAS No.	1378332-54-7
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-2-pyrazinylacetonitrile; (6-Chloro-2-pyrazinyl)acetonitrile; 2-(6-Chloro-2-pyrazinyl)acetonitrile; 2-(6-Chloropyrazin-2-yl)ethanenitrile; Acetonitrile, 2-(6-chloro-2-pyrazinyl)-; 1378332-54-7; 6-Chloropyrazine-2-acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(6-Chloropyrazin-2-Yl)Acetonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. Our quality commitment supports compliance in cGMP and ISO environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.