Description

1-(Thiolan-3-Yl)Piperazine Dihydrochloride is a high-purity, specialized organic salt used as a critical building block in advanced chemical synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmaceutical candidates and complex organic molecules. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Chemical Synthesis Building Block: Serves as a bifunctional intermediate for introducing the piperazine-thiolane moiety into more complex molecular architectures.
• Ligand and Catalyst Development: Potential use in the preparation of specialized ligands for metal catalysis or in materials science applications.
• Academic and Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	1-(Thiolan-3-Yl)Piperazine Dihydrochloride
CAS No.	1376228-74-8
Molecular Formula	C8H18Cl2N2S
Molecular Weight	245.21 g/mol
Synonyms	1-(Tetrahydrothiophen-3-yl)piperazine dihydrochloride; 3-Piperazin-1-ylthiolane dihydrochloride; 1-(Thiolan-3-yl)piperazine hydrochloride (1:2); Tetrahydro-3-(1-piperazinyl)thiophene dihydrochloride; 1-(Thiolan-3-yl)piperazine dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 1-(Thiolan-3-Yl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.