Description

6-Chloro-3-Hydroxypyrazine-2-Carbonitrile is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its unique pyrazine core functionalized with chloro, hydroxy, and cyano groups makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting various disease pathways.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis: Versatile building block for constructing more complex nitrogen-containing heterocycles in medicinal and process chemistry.
• Bioconjugation & Probe Development: Utilized in designing molecular probes and linker molecules for biochemical and diagnostic applications.

Basic Information

Product Name	6-Chloro-3-Hydroxypyrazine-2-Carbonitrile
CAS No.	1374986-27-2
Molecular Formula	C5H2ClN3O
Molecular Weight	155.54 g/mol
Synonyms	6-Chloro-3-hydroxypyrazine-2-carbonitrile; 2-Pyrazinecarbonitrile, 6-chloro-3-hydroxy-; 3-Hydroxy-6-chloropyrazine-2-carbonitrile; 6-Chloro-3-oxo-3,4-dihydropyrazine-2-carbonitrile; 6-Chloro-3-pyrazinolcarbonitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Hydroxypyrazine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.