Description

5-Fluoro-Isoxazolo[4,5-B]Pyrazine-3-Carboxylic Acid Methyl Ester is a high-value, fluorinated heterocyclic building block critical for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the fluorinated isoxazolopyrazine core.
• Material Science Precursor: Serves as a building block for creating specialized organic electronic materials or ligands for catalysis.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new heterocyclic chemistry.
• Library Synthesis: Ideal for generating diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	5-Fluoro-Isoxazolo[4,5-B]Pyrazine-3-Carboxylic Acid Methyl Ester
CAS No.	1374986-06-7
Molecular Formula	C8H5FN4O3
Molecular Weight	224.15 g/mol
Synonyms	Methyl 5-fluoroisoxazolo[4,5-b]pyrazine-3-carboxylate; 5-Fluoro-3-(methoxycarbonyl)isoxazolo[4,5-b]pyrazine; 5-Fluoro-isoxazolo[4,5-b]pyrazine-3-carboxylic acid methyl ester; Isoxazolo[4,5-b]pyrazine-3-carboxylic acid, 5-fluoro-, methyl ester; 1374986-06-7; 5-Fluoroisoxazolopyrazine methyl ester; 5-Fluoro-3-carbomethoxyisoxazolo[4,5-b]pyrazine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-Isoxazolo[4,5-B]Pyrazine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.