Description

6-Bromo-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic pyrazinone class. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening against various biological targets.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes to study enzyme function and cellular pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for candidate drugs.

Basic Information

Product Name	6-Bromo-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS No.	1374684-64-6
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-one; 6-Bromo-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 1374684-64-6; 6-Bromotetrahydropyrrolopyrazinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.