Description

(R)-tert-Butyl 2-Methyl-1,4-Diazepane-1-Carboxylate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision. This compound is essential for research and production chemists in the pharmaceutical and biotechnology industries who are developing new drug candidates, especially those targeting central nervous system (CNS) disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for the research and development of new therapeutic compounds, particularly in CNS and neurological applications.
• Asymmetric Synthesis: Serves as a valuable precursor in catalytic and stoichiometric asymmetric synthesis due to its defined stereochemistry.
• Peptidomimetic Chemistry: The diazepane scaffold is utilized in the design and synthesis of peptidomimetics and conformationally constrained analogs.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	(R)-tert-Butyl 2-Methyl-1,4-Diazepane-1-Carboxylate
CAS No.	1374130-05-8
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1,4-Diazepane-1-carboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2R)-; tert-Butyl (2R)-2-methyl-1,4-diazepane-1-carboxylate; (R)-tert-Butyl 2-methyl-1,4-diazepane-1-carboxylate; (R)-2-Methyl-1,4-diazepane-1-carboxylic acid tert-butyl ester; Boc-(R)-2-methyl-1,4-diazepane; (R)-Boc-2-methylhomopiperazine; (R)-1-Boc-2-methyl-1,4-diazepane
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 2-Methyl-1,4-Diazepane-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All products undergo rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.