Description

(S)-Benzyl 2-Methyl-3-Oxopiperazine-1-Carboxylate is a high-purity chiral piperazine derivative serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its primary value lies in enabling the stereoselective construction of complex molecules, which is essential for creating novel therapeutic agents with targeted biological activity. This compound is specifically needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• API Synthesis: Used in the development and scale-up of Active Pharmaceutical Ingredients (APIs) requiring a stereochemically defined piperazine core.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Serves as a starting material or advanced intermediate in the development of efficient, scalable synthetic routes under GMP conditions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereocontrolled chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals and complex organic molecules for research and commercial supply.

Basic Information

Product Name	(S)-Benzyl 2-Methyl-3-Oxopiperazine-1-Carboxylate
CAS No.	1373232-22-4
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	(S)-1-Benzyloxycarbonyl-2-methyl-3-oxopiperazine; (S)-1-CBZ-2-Methyl-3-oxopiperazine; (S)-Benzyl 2-methyl-3-oxo-1-piperazinecarboxylate; (S)-1-(Benzyloxycarbonyl)-2-methylpiperazine-3-one; (S)-N-CBZ-2-Methyl-3-oxopiperazine; (3S)-1-[(Benzyloxy)carbonyl]-2-methyl-3-oxopiperazine; 1-Piperazinecarboxylic acid, 2-methyl-3-oxo-, phenylmethyl ester, (2S)-; BOC-Piperazine Derivative (S)-enantiomer.
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Methyl-3-Oxopiperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.