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3-Bromo-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrazine Dihydrochloride CAS NO 1373223-47-2
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CAS No.:1373223-47-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrazine Dihydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its functionalized pyrazolo[1,5-a]pyrazine core, which is a privileged scaffold for designing novel bioactive molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of potential drug candidates targeting a range of therapeutic areas.
Application
- Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
- Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile bromine handle for further functionalization.
- Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides with enhanced efficacy.
- Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.
- Academic Research: Employed in university and institutional laboratories for fundamental studies in heterocyclic chemistry and new synthetic methodology development.
Basic Information
| Product Name | 3-Bromo-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrazine Dihydrochloride |
| CAS No. | 1373223-47-2 |
| Molecular Formula | C7H12BrCl2N3 |
| Molecular Weight | 289.00 g/mol |
| Synonyms | 3-Bromo-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrazine dihydrochloride; 3-Bromo-1,4,5,6,7,8-hexahydropyrazolo[1,5-a]pyrazine dihydrochloride; 3-Bromo-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrazine dihydrochloride; 3-Bromotetrahydropyrazolopyrazine dihydrochloride; Pyrazolo[1,5-a]pyrazine, 3-bromo-4,5,6,7-tetrahydro-, dihydrochloride |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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