Description

Benzyl 3-((tert-Butoxycarbonyl)Amino)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing novel heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting protein kinases and other enzymatic pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new compounds with improved efficacy and safety profiles.
• API Synthesis: Serves as a crucial precursor in the production of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Heterocyclic Chemistry: Exploited for constructing fused pyrazolo-pyrazine ring systems, which are privileged structures in modern drug discovery.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent high purity and reliable supply.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Benzyl 3-((tert-Butoxycarbonyl)Amino)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate
CAS No.	1373028-73-9
Molecular Formula	C20H26N4O4
Molecular Weight	386.45 g/mol
Synonyms	Benzyl 3-((Boc)Amino)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate; 5H-6,7-Dihydropyrazolo[1,5-a]pyrazine-5-carboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, phenylmethyl ester; Benzyl 3-(Boc-amino)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate; tert-Butyl N-[5-(benzyloxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]carbamate; BOC-Protected Pyrazolo-Pyrazine Intermediate
EINECS	Contact for details

Quality Control

Our Benzyl 3-((tert-Butoxycarbonyl)Amino)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.