Description

4-Methyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl trifluoromethanesulfonate (Wx682941) is a high-value triflate ester derivative of a fused bicyclic heterocycle, serving as a critical synthetic intermediate. Its core value lies in providing a reactive handle for advanced cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those containing the privileged cyclopentapyridine scaffold.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with potentially enhanced efficacy.
• Material Science: Precursor for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Catalysis & Ligand Synthesis: Serves as a starting point for developing novel palladium ligands or organocatalysts.
• Cross-Coupling Reactions: The triflate group is an excellent leaving group for Suzuki, Stille, and Negishi couplings to introduce the heterocyclic moiety.
• Chemical Biology Probes: Used to create tagged or modified molecules for studying biological pathways and target engagement.

Basic Information

Product Name	4-Methyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl trifluoromethanesulfonate (Wx682941)
CAS No.	1373028-22-8
Molecular Formula	C10H10F3NO3S
Molecular Weight	281.25 g/mol
Synonyms	2-(Trifluoromethanesulfonyloxy)-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine; 4-Methyl-5,6-dihydrocyclopenta[b]pyridin-2-yl triflate; 4-Methyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl triflate; WX-682941; Wx682941; 2-Triflyloxy-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Methyl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.