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Deoxynivalenol 15-Glucuronide CAS NO 1372859-16-9


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CAS No.:1372859-16-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Deoxynivalenol 15-Glucuronide is a crucial conjugated metabolite of the mycotoxin deoxynivalenol (DON, vomitoxin). This compound is essential for accurate analytical quantification and toxicological studies of DON exposure in food, feed, and biological samples. It serves as a primary reference standard for laboratories in the food safety, agricultural, and life science research sectors, enabling precise calibration and method validation.

Application

  • Analytical Reference Standard: Primary use as a certified reference material (CRM) for the quantification of DON-15-GlcA in complex matrices via LC-MS/MS, HPLC, or ELISA.
  • Food & Feed Safety Testing: Calibration standard for monitoring DON and its masked mycotoxins in grains (wheat, barley, corn), cereals, and animal feed to ensure regulatory compliance.
  • Biomarker Research: Critical for developing and validating analytical methods to detect this specific glucuronide conjugate as a biomarker of DON exposure in urine and plasma for human and animal health studies.
  • Toxicology & Metabolism Studies: Used in research to investigate the detoxification pathways, pharmacokinetics, and comparative toxicity of DON and its metabolites.
  • Method Development & Validation: Essential for laboratories establishing or accrediting (ISO/IEC 17025) analytical methods for mycotoxin testing, ensuring accuracy and traceability.
  • Quality Control & Assurance: Used as an internal standard or spike-in control for assay precision and recovery rate calculations in commercial testing laboratories.

Basic Information

Product Name Deoxynivalenol 15-Glucuronide
CAS No. 1372859-16-9
Molecular Formula C21H28O13
Molecular Weight 488.44 g/mol
Synonyms DON-15-GlcA; DON-15-Glucuronide; Vomitoxin-15-Glucuronide; 15-Glucuronide of Deoxynivalenol; 3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one 15-β-D-Glucopyranosiduronic Acid; Deoxynivalenol 15-O-β-D-Glucuronide; 15-Glucuronyl-deoxynivalenol
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Quality Control

Every batch of Deoxynivalenol 15-Glucuronide is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that include data for identity, purity (HPLC), and specific tests for related substances. Our quality system ensures traceability and consistency, supporting compliance with standards relevant to reference material producers and GMP/GLP laboratory environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms to reference standard
Assay (HPLC) ≥ 95.0%
Purity (HPLC, Area%) ≥ 98.0%
Related Substances (HPLC) Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in methanol, acetonitrile; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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