Description

Dinophysistoxin 2 (DTX2) is a potent marine biotoxin belonging to the lipophilic okadaic acid group, identified by CAS NO 139933-46-3. This compound is of critical importance for research, regulatory compliance, and food safety monitoring due to its role in Diarrhetic Shellfish Poisoning (DSP). It is primarily needed by analytical laboratories, regulatory agencies, and pharmaceutical research institutions focused on toxin detection, mechanism of action studies, and the development of reference standards and diagnostic assays.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the accurate quantification of DSP toxins in shellfish and seawater via LC-MS/MS, HPLC, and ELISA methods.
• Food Safety & Regulatory Testing: Essential for calibrating equipment and validating methods in national monitoring programs to ensure compliance with maximum permitted levels in seafood.
• Toxicological Research: Used in academic and pharmaceutical research to study the inhibition of protein phosphatases (PP1 and PP2A), cellular toxicity, and the mechanisms of DSP.
• Diagnostic Kit Development: Serves as a key antigen for the production and validation of immunoassay-based rapid test kits for on-site shellfish toxicity screening.
• Environmental Monitoring: Employed in oceanography and ecology studies to monitor harmful algal blooms (HABs) of dinoflagellates like *Dinophysis* spp.
• Method Development & Validation: Critical for laboratories establishing or accrediting (ISO/IEC 17025) new analytical procedures for lipophilic marine biotoxins.

Basic Information

Product Name	Dinophysistoxin 2
CAS No.	139933-46-3
Molecular Formula	C₄₁H₆₄O₁₃
Molecular Weight	764.9 g/mol
Synonyms	DTX2; 35(S)-Methylokadaic acid; Dinophysistoxin-2; 35-Methylokadaic acid; (2S,3aR,4S,5R,5aR,9aS,10R,10aS,11S,11aR,11bS)-10-[(1R)-1-Carboxyethyl]-5,11-dihydroxy-2,4,9a,11b-tetramethyl-1,2,3,3a,4,5,5a,9,9a,10,10a,11,11a,11b-tetradecahydro-7H-5a,11b-epoxynaphtho[2,1-f]oxireno[4,5-d]oxacyclotridecine-7,8-dione
EINECS	Contact for details

Quality Control

Our Dinophysistoxin 2 is produced and handled under strict quality protocols suitable for high-purity reference standards. Each batch undergoes rigorous identity confirmation and purity analysis. A comprehensive Certificate of Analysis (COA) is provided, detailing results from advanced chromatographic and spectroscopic methods. Our quality system supports compliance with standards relevant to reference material producers and analytical laboratories.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. The material should be stored in a dedicated freezer for toxins and handled in accordance with laboratory safety protocols.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time matches CRM
Identification (MS)	Mass spectrum conforms
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.