Description

tert-Butyl 5-Oxo-3,4-Dipropyl-5,6-Dihydropyridine-1(2H)-Carboxylate CAS NO 1372173-47-1 is a high-purity, advanced pharmaceutical intermediate characterized by its specific dihydropyridine core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and manufacturers of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its functionalized dihydropyridine scaffold.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Fine Chemical Production: Utilized in the synthesis of complex, high-value specialty chemicals beyond pharmaceuticals.

Basic Information

Product Name	tert-Butyl 5-Oxo-3,4-Dipropyl-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	1372173-47-1
Molecular Formula	C16H27NO3
Molecular Weight	281.39 g/mol
Synonyms	1,2-Dihydro-5-oxo-3,4-dipropylpyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 5-oxo-3,4-dipropyl-1,2-dihydro-1-pyridinecarboxylate; 3,4-Dipropyl-5-oxo-1,2-dihydropyridine-1-carboxylic acid tert-butyl ester; 1-Boc-3,4-dipropyl-5-oxo-1,2-dihydropyridine; 5-Oxo-3,4-dipropyl-1,2-dihydropyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 3,4-dipropyl-5-oxo-1,2-dihydropyridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Oxo-3,4-Dipropyl-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.