Description

5-Ethynyl-2-Methoxy-3-Methylpyridine is a high-purity pyridine derivative featuring a reactive ethynyl group, making it a valuable building block in advanced organic synthesis. This compound is critical for the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Research: Used as a precursor in developing novel herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a building block for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic electronic materials, conductive polymers, and advanced polymers.
• Chemical Biology Probes: Utilized in click chemistry applications for bioconjugation and labeling of biomolecules.
• Academic & Industrial R&D: A versatile reagent for exploratory chemistry and process optimization in laboratory-scale and pilot-scale synthesis.

Basic Information

Product Name	5-Ethynyl-2-Methoxy-3-Methylpyridine
CAS No.	1372100-25-8
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	2-Methoxy-3-methyl-5-ethynylpyridine; 3-Methyl-2-methoxy-5-ethynylpyridine; 5-Ethynyl-2-methoxy-3-picoline; 5-Ethynyl-3-methyl-2-methoxypyridine
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Methoxy-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.