Description

4-Iodo-2-(Morpholino)Pyridine is a versatile heterocyclic building block featuring a halogenated pyridine core functionalized with a morpholine substituent. This compound is of significant value in medicinal chemistry and materials science for its role as a key intermediate in cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated structure for further functionalization.
• Material Science: Serves as a building block for creating organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Ligand Preparation: Useful for synthesizing novel chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Acts as a biochemical tool compound for probing biological pathways and enzyme functions.

Basic Information

Product Name	4-Iodo-2-(Morpholino)Pyridine
CAS No.	1370025-59-4
Molecular Formula	C9H11IN2O
Molecular Weight	290.10 g/mol
Synonyms	2-Morpholino-4-iodopyridine; 4-Iodo-2-morpholinopyridine; 4-Iodo-2-(4-morpholinyl)pyridine; Pyridine, 4-iodo-2-(4-morpholinyl)-; 1370025-59-4; 4-Iodo-2-morpholino pyridine
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-(Morpholino)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.