Description

6-Chloro-3-Fluoropyridin-2-Ol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique halogenated structure makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for developing active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the development of advanced organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial labs.
• Ligand and Catalyst Preparation: Serves as a precursor for creating novel ligands used in homogeneous catalysis.

Basic Information

Product Name	6-Chloro-3-Fluoropyridin-2-Ol
CAS No.	1369769-03-8
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	2-Hydroxy-6-chloro-3-fluoropyridine; 3-Fluoro-6-chloropyridin-2-ol; 6-Chloro-3-fluoro-2-pyridinol; 6-Chloro-3-fluoro-2(1H)-pyridinone; 2-Chloro-5-fluoro-6-hydroxypyridine; 6-Chloro-3-fluoro-2-hydroxypyridine; 2-Pyridinol, 6-chloro-3-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Fluoropyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.