Description

2-(Piperidin-3-Yl)Pyrazine Dihydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical research and development. Its molecular architecture, combining piperidine and pyrazine motifs, makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of new drug candidates, especially in neuroscience and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular tools to study biological pathways and protein function.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-(Piperidin-3-Yl)Pyrazine Dihydrochloride
CAS No.	1369367-37-2
Molecular Formula	C9H14Cl2N3
Molecular Weight	235.13 g/mol
Synonyms	2-(3-Piperidyl)pyrazine dihydrochloride; Pyrazine, 2-(3-piperidinyl)-, dihydrochloride; 3-(Pyrazin-2-yl)piperidine dihydrochloride; 2-(Piperidin-3-yl)pyrazine hydrochloride (1:2); 2-Piperidin-3-ylpyrazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-3-Yl)Pyrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.