Description

8-Bromo-[1,2,4]triazolo[1,5-a]pyrazine is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmaceuticals and agrochemicals, particularly in the creation of compounds with specific biological activity. This compound is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry and material science. Its precise reactivity profile enables the construction of complex molecular architectures that are otherwise difficult to access.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for creating novel organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.
• Dye & Pigment Synthesis: Functions as an intermediate in the production of specialized dyes and functional pigments due to its aromatic system.

Basic Information

Product Name	8-Bromo-[1,2,4]triazolo[1,5-a]pyrazine
CAS No.	1367824-76-7
Molecular Formula	C5H3BrN4
Molecular Weight	198.01 g/mol
Synonyms	8-Bromo-[1,2,4]triazolopyrazine; 8-Bromo-1,2,4-triazolo[1,5-a]pyrazine; [1,2,4]Triazolo[1,5-a]pyrazine, 8-bromo-; 1367824-76-7; 8-Bromo-1,2,4-triazolo[1,5-a]pyrazine; 8-Bromotriazolopyrazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-[1,2,4]triazolo[1,5-a]pyrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications, and we can support custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.