Description

2-Piperazinecarboxylic Acid, 1-(1-Methylethyl)- is a specialized piperazine derivative, a key chiral building block in advanced organic synthesis. Its value lies in its structural complexity, which is essential for constructing sophisticated molecular architectures with high stereochemical control. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise chirality is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Peptidomimetics Research: Incorporated into the backbone of peptide analogs to modulate biological activity, stability, and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific, high-value compounds under cGMP conditions.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and the synthesis of complex natural product analogs.

Basic Information

Product Name	2-Piperazinecarboxylic Acid, 1-(1-Methylethyl)-
CAS No.	1367734-02-8
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	1-Isopropylpiperazine-2-carboxylic Acid; (S)-1-Isopropylpiperazine-2-carboxylic Acid (if enantiomerically pure); 1-(Propan-2-yl)piperazine-2-carboxylic Acid; 1-(1-Methylethyl)-2-piperazinecarboxylic Acid; 2-Carboxy-1-isopropylpiperazine; NSC 760463; A chiral piperazinecarboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarboxylic Acid, 1-(1-Methylethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.