Description

6-Chloro-3-Nitro-1,5-Naphthyridin-4-Ol is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of novel pharmaceutical compounds and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A versatile precursor in the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for biological activity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a key scaffold for further functionalization (e.g., cross-coupling reactions) to create diverse chemical libraries for screening.
• Academic Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	6-Chloro-3-Nitro-1,5-Naphthyridin-4-Ol
CAS No.	1366050-42-1
Molecular Formula	C8H4ClN3O3
Molecular Weight	225.59 g/mol
Synonyms	6-Chloro-3-nitro-1,5-naphthyridin-4-ol; 4-Hydroxy-6-chloro-3-nitro-1,5-naphthyridine; 1,5-Naphthyridin-4-ol, 6-chloro-3-nitro-; 6-Chloro-3-nitro-4-hydroxy-1,5-naphthyridine; 1366050-42-1; 6-Chloro-3-nitro-1,5-naphthyridin-4(1H)-one (tautomer); 4-Chloro-7-nitro-1,8-naphthyridin-5-ol (alternative numbering)
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Nitro-1,5-Naphthyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.