Description

[1-(Pyrazin-2-Yl)Piperidin-4-Yl]Methanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1365988-46-0. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small molecule drugs targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes to study biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	[1-(Pyrazin-2-Yl)Piperidin-4-Yl]Methanamine Dihydrochloride
CAS No.	1365988-46-0
Molecular Formula	C10H18Cl2N4
Molecular Weight	265.18 g/mol
Synonyms	1-(Pyrazin-2-yl)piperidin-4-ylmethanamine dihydrochloride; 4-(Aminomethyl)-1-(pyrazin-2-yl)piperidine dihydrochloride; 1-Pyrazin-2-ylpiperidine-4-methanamine dihydrochloride; (1-(Pyrazin-2-yl)piperidin-4-yl)methanamine dihydrochloride; 1365988-46-0; UNII-7K8J8U6Y7I; 7K8J8U6Y7I; CHEMBL3185223
EINECS	Contact for details

Quality Control

Our [1-(Pyrazin-2-Yl)Piperidin-4-Yl]Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.