Description

(1R*,4R*)-1-n-(Pyrazin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride is a high-purity, stereochemically defined diamine derivative used as a critical building block in advanced chemical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemical applications where precise stereochemistry is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in stereoselective synthesis routes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Agrochemical Research: Potential intermediate in the development of novel, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	(1R*,4R*)-1-n-(Pyrazin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride
CAS No.	1365968-52-0
Molecular Formula	C11H19N5 · 2HCl
Molecular Weight	310.22 g/mol (free base: 221.30 g/mol)
Synonyms	(1R*,4R*)-1-(Pyrazin-2-yl)cyclohexane-1,4-diamine dihydrochloride; (1R,4R)-1-(Pyrazin-2-yl)cyclohexane-1,4-diamine dihydrochloride; 1-(Pyrazin-2-yl)cyclohexane-1,4-diamine dihydrochloride (racemic); 1,4-Diamino-1-(2-pyrazinyl)cyclohexane dihydrochloride; 1-(2-Pyrazinyl)-1,4-diaminocyclohexane dihydrochloride; Pyrazine-cyclohexanediamine dihydrochloride; CAS 1365968-52-0
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-1-n-(Pyrazin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99:1 dr (1R*,4R*)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.