Description

(1R*,4R*)-tert-Butyl n-[4-(Pyrazin-2-Ylamino)Cyclohexyl]Carbamate is a high-purity, stereochemically defined chemical intermediate of significant importance in modern pharmaceutical research and development. Its value lies in its role as a key building block for synthesizing complex molecules, particularly in the creation of novel active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists working in pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• API Synthesis: Used in the research and process development stages for constructing complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Peptidomimetic Development: Its cyclohexyl and carbamate structure makes it suitable for developing peptide-like compounds with enhanced metabolic stability.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.

Basic Information

Product Name	(1R*,4R*)-tert-Butyl n-[4-(Pyrazin-2-Ylamino)Cyclohexyl]Carbamate
CAS No.	1365968-46-2
Molecular Formula	C15H24N4O2
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl (1R,4R)-4-[(pyrazin-2-yl)amino]cyclohexylcarbamate; (1R,4R)-N-(tert-Butoxycarbonyl)-4-(pyrazin-2-ylamino)cyclohexanamine; 4-[(Pyrazin-2-yl)amino]cyclohexylcarbamic acid tert-butyl ester; (1R,4R)-4-(Pyrazin-2-ylamino)cyclohexyl-carbamic acid tert-butyl ester; BOC-protected 4-(pyrazin-2-ylamino)cyclohexylamine (trans isomer); trans-tert-Butyl 4-((pyrazin-2-yl)amino)cyclohexylcarbamate
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-tert-Butyl n-[4-(Pyrazin-2-Ylamino)Cyclohexyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D applications. Certificates of Analysis (COA) detailing specifications such as chiral purity, chemical purity (HPLC), and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored accordingly to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.