Description

(3R)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is a high-purity chiral amine salt, serving as a critical pharmaceutical intermediate and building block in organic synthesis. Its value lies in providing a stereochemically defined scaffold essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Organic Synthesis Reagent: Used in asymmetric synthesis and as a precursor for more complex nitrogen-containing heterocycles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in metal-catalyzed asymmetric transformations.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with specific stereochemical requirements.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Academic & Contract Research: Essential material for research in synthetic methodology and medicinal chemistry within academic and CRO settings.

Basic Information

Product Name	(3R)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride
CAS No.	1365937-15-0
Molecular Formula	C8H13N5 · 2HCl
Molecular Weight	268.14 g/mol
Synonyms	(R)-1-(Pyrazin-2-yl)pyrrolidin-3-amine dihydrochloride; (3R)-1-Pyrazin-2-ylpyrrolidin-3-amine dihydrochloride; (R)-1-(2-Pyrazinyl)-3-pyrrolidinamine dihydrochloride; 1365937-15-0; (R)-1-(Pyrazin-2-yl)pyrrolidin-3-amine hydrochloride (1:2); (R)-3-Amino-1-(pyrazin-2-yl)pyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our (3R)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.