Description

tert-Butyl n-[(3S)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Yl]Carbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex target molecules, leveraging its protected amine and pyrrolidine-pyrazine scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry: Serves as a standardized starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized in reactions where the (S)-configuration of the pyrrolidine ring is essential for biological activity.

Basic Information

Product Name	tert-Butyl n-[(3S)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Yl]Carbamate
CAS No.	1365936-65-7
Molecular Formula	C13H20N4O2
Molecular Weight	264.33 g/mol
Synonyms	Carbamic acid, N-[(3S)-1-(2-pyrazinyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester; tert-Butyl (S)-(1-(pyrazin-2-yl)pyrrolidin-3-yl)carbamate; (S)-tert-Butyl (1-(pyrazin-2-yl)pyrrolidin-3-yl)carbamate; Boc-(S)-3-Amino-1-(pyrazin-2-yl)pyrrolidine; (S)-1-(Pyrazin-2-yl)pyrrolidin-3-yl-carbamic acid tert-butyl ester; (S)-3-((tert-Butoxycarbonyl)amino)-1-(pyrazin-2-yl)pyrrolidine; (S)-N-Boc-3-amino-1-(2-pyrazinyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(3S)-1-(Pyrazin-2-Yl)Pyrrolidin-3-Yl]Carbamate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All products undergo rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.