Description

1,3-Dimethyl 2-(5-Bromo-3-Cyanopyridin-2-Yl)Propanedioate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyridine and diester functional groups. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing more complex molecules in organic and medicinal chemistry laboratories.
• Material Science Research: Potential use in the development of specialty chemicals and functional materials due to its unique molecular architecture.

Basic Information

Product Name	1,3-Dimethyl 2-(5-Bromo-3-Cyanopyridin-2-Yl)Propanedioate
CAS No.	1365271-81-3
Molecular Formula	C12H9BrN2O4
Molecular Weight	325.12 g/mol
Synonyms	Dimethyl 2-(5-bromo-3-cyano-2-pyridinyl)propanedioate; Propanedioic acid, 2-(5-bromo-3-cyano-2-pyridinyl)-, 1,3-dimethyl ester; 5-Bromo-3-cyano-2-pyridinylmalonic acid dimethyl ester; 1,3-Dimethyl (5-bromo-3-cyanopyridin-2-yl)malonate; (5-Bromo-3-cyanopyridin-2-yl)malonic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl 2-(5-Bromo-3-Cyanopyridin-2-Yl)Propanedioate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.