Description

5-Chloro-3-(Trifluoromethyl)Pyrazin-2-Amine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced chemical synthesis. Its core value lies in the unique reactivity imparted by the combination of chloro, trifluoromethyl, and amine substituents on the pyrazine ring, enabling precise molecular construction. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine core.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics and specialty polymers.
• Chemical Biology: Employed as a molecular probe or a building block for labeled compounds in biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex heterocyclic architectures.

Basic Information

Product Name	5-Chloro-3-(Trifluoromethyl)Pyrazin-2-Amine
CAS No.	1364663-32-0
Molecular Formula	C5H3ClF3N3
Molecular Weight	197.55 g/mol
Synonyms	2-Amino-5-chloro-3-(trifluoromethyl)pyrazine; 5-Chloro-3-(trifluoromethyl)-2-pyrazinamine; 5-Chloro-3-trifluoromethylpyrazin-2-ylamine; 1364663-32-0; 2-Pyrazinamine, 5-chloro-3-(trifluoromethyl)-; 5-Chloro-3-(trifluoromethyl)pyrazin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-(Trifluoromethyl)Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.